Following the previous meetings in Florence and Hilton Head, the 3rd Biennial Meeting will focus on recent advances in valve biology and the development of tissue engineered heart valve replacements. The programme has been designed to reflect the diversity of challenges faced by biologists, bioengineers, material scientists, clinicians and regulators and the multidisciplinary approach that is required for successful tissue engineering of heart valves. The purpose is to provide a forum for presentation and discussion of cutting edge technology and recent advances in this field.